telepathy-python ships with a number of example applications demonstrating how to use various parts of the Telepathy API:
In the source, they're in the examples/ directory;
In the Debian package, they're in /usr/share/doc/python-telepathy/examples/;
You could also browse them in gitweb.
The DTube Tutorial and its example are written in Python.
In addition, the Telepathy Developer's Manual contains some examples on using telepathy-python. You may also want to consult the dbus-python tutorial, since telepathy-python is based on dbus-python.