Managing contact information, commonly known as the "roster", is a big part most clients. This includes handling things like a contact's real name, presence and status, avatar and client capabilities.
A list of handles usually comes from a channel with the Group interface (i.e. a chatroom or a contact list).
In general, a client will connect the relevant signals to receive updates for presence, aliases, avatars, capabilities, and so on; and then use the Contacts interface to bulk request the intial state.